User Manual
This document demonstrates the reproducibility and reliability of the Varian 320-MS triple quadrupole mass spectrometer in analyzing complex samples. By using the 212-LC binary gradient LC/MS chromatography pumps, the instrument can achieve excellent reproducibility of both area and retention time over multiple injections. The method was tested on a heavy matrix containing multiple components and transitions, showing excellent reliability and reproducibility of the system. The document also describes the specific steps and experimental conditions for analyzing samples extracted from tomato, orange, spinach, sweet corn, and raisin matrices using the QUECHERS method. The experimental results show that the % RSD of Buprofezin (306 ➔ 201) retention time is 0.02 and 0.09 over 60 and 100 subsequent injections, respectively, demonstrating the reliability of the system.
User Manual
This document introduces Varian 320-MS, a triple quadrupole mass spectrometer with a unique 180° off-axis collision cell and triple quadrupole configuration. This instrument can eliminate chemical background noise and cross-talk when similar product ions in complex matrices are monitored in the same time segment.
User Manual
User Manual
Varian's 320-MS triple quadrupole system meets the quality guidelines for qualifier assessment and ion ratio stability set by the European Union for the detection and analysis of toxic compounds.
User Manual
Varian 320-ms is the latest generation of triple quadrupole mass spectrometers from Varian. It is easy to use and flexible. It can meet the needs of different users.
Application Note
This document introduces a method for quantifying multi-class pharmaceuticals in water using simultaneous positive and negative ESI on the Varian 320-MS triple quadrupole mass spectrometer
Application Note
EtG is a minor metabolite of ethanol, can be detected in blood for up to 36 hours and in urine for up to 5 days, can be used as a biomarker for alcohol consumption. This application note describes a fast and sensitive EtG analysis method using the Varian Pursuit C18 HPLC column and 320-MS LC/MS/MS system, which demonstrates good linearity, high sensitivity, and stable ion ratios with a detection limit of 10 ppb.
Application Note
This application note describes the use of the Varian 320-MS Triple Quadrupole LC/MS/MS for the analysis of 15 azo dyes. This method provides high sensitivity, accuracy and selectivity, making it a useful tool for regulatory monitoring and quality assessment.
Application Note
This application note describes a method for the direct aqueous injection and automated on-line solid phase extraction (SPE) analysis of phenoxy herbicides in drinking water using the Varian 320-MS triple quadrupole LC/MS/MS. The method provides high sensitivity, selectivity, and analysis speed, meeting the requirements for trace-level quantitation of phenoxy herbicides in drinking water.
Application Note
This article describes the application of Varian's 320-MS triple quadrupole LC/MS/MS system in the direct aqueous injection and automated on-line solid phase extraction (SPE) analysis of phenoxy herbicides in drinking water. Phenoxy herbicides are a class of chemicals related to the growth hormone indoleacetic acid. Contact with broad-leaf plants induces rapid, uncontrolled growth, killing the affected plants. Phenoxy herbicides are widely used to selectively destroy broad-leaved weeds amongst wheat or corn crops. The best-known phenoxy herbicides are 2,4-dichlorophenoxy-acetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). 2,4,5-T itself is only moderately toxic, with an oral LD50 of 389 mg/kg. However, the manufacturing process for 2,4,5-T contaminates this chemical with trace amounts of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is reported to be extremely toxic to humans. 2,4-D has not been reported as being contaminated with TCDD, however it is one of the most widely used herbicides in the world and is a regulated drinking water contaminant in the United States and other countries.
Application Note
This application note demonstrates how phospholipids can be identified in a mixture by triple quadrupole mass spectrometry and suspected structures confirmed by generating MS/MS spectra and submitting it to the ACD Labs/MS Manager software.
Application Note
This document introduces an antibiotic called Lasalocid, which belongs to a group of antibiotics known as ionophores and can be used in the prophylaxis and treatment of coccidiosis and leukocytozoonosis in poultry. The document focuses on the ability of the Varian 320-MS Triple Quadrupole Mass Spectrometer to detect Lasalocid in animal feed.
User Manual
This paper introduces a method for detecting low levels of tylosin using a 320-MS triple quadrupole mass spectrometer. This method can accurately detect and quantify tylosin over a wide concentration range and below EU required tolerance limits.
User Manual
This application note describes a method for the detection of oxytetracycline and chlorotetracycline in animal feed and tissue extracts using the 320-MS Triple Quadrupole Mass Spectrometer.
User Manual
This document describes a method for quantitative analysis of the herbicide imazaquin on the Varian 320-MS Triple Quadrupole LC/MS/MS. The method is highly sensitive, selective and accurate, and can detect imazaquin at trace levels.
