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Agilent 1260 Infinity Hybrid SFC/UHPLC System Technical Overview
The Agilent 1260 Infinity Hybrid SFC/UHPLC system is a unique solution designed to perform both supercritical fluid chromatography (SFC) and ultrahigh performance liquid chromatography (UHPLC) on a single platform. This hybrid configuration allows for orthogonal separation techniques, providing different selectivity compared to standard reversed-phase separation, which is ideal for purity analyses and impurity profiling. The system eliminates the need for two separate instruments, saving laboratory space and cost while ensuring consistent results across different modes.
Read onlineAgilent 1260 Infinity Hybrid SFC specifications
| Power Range | 600-bar |
|---|---|
| SFC Backpressure Regulator Setting | 150 bar |
| UHPLC Backpressure Regulator Setting | 90 bar |
| SFC Flow Rate | 3 mL/min |
| UHPLC Flow Rate | 1.5 mL/min |
Source: Agilent 1260 Infinity Hybrid SFC/UHPLC System Technical Overview
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How to use the product for one specific task, with worked examples.
Questions answered in these manuals
Can existing Agilent HPLC systems be upgraded to a hybrid system?
Yes, existing Agilent HPLC and SFC systems can be easily upgraded to a hybrid SFC/UHPLC system.
From: Agilent 1260 Infinity Hybrid SFC/UHPLC System Technical Overview
What is the maximum pressure range for the hybrid system?
The system facilitates analyses in SFC or UHPLC mode up to pressures of 600 bar.
From: Agilent 1260 Infinity Hybrid SFC/UHPLC System Technical Overview
What is the SFC flow rate used for the prednisolone method?
The SFC flow rate is maintained at 2.9 mL/min.
What is the run time for the SFC method?
The SFC run time is 5.5 minutes.