Key facts
Start here
Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet
The Agilent 6410 triple quadrupole mass spectrometer combined with BioTrove's RapidFire system provides an integrated solution for high-throughput preparation and analysis of in vitro biological assays in pharmaceutical drug research. This native detection technology allows researchers to obtain mass spectrometry-based data in a fraction of the time needed for traditional LC-MS techniques, specifically for screening Cytochrome P450 (CYP) interactions.
Read onlineAgilent 6410 Triple Quadrupole specifications
| Sample Throughput | Over 3,500 samples/instrument/shift |
|---|---|
| Plate Format | SBS standard 96 or 384-well plates |
| Sample Processing | On-line clean-up permits direct sampling |
| Ionization Modes | ESI, APCI and multimode |
| Weight | 170 kg (875 lbs) |
| Footprint | 152 x 183 x 76 cm (WxHxD) |
| Electrical Requirements | 115 V, 60 Hz, 15 AMP |
| Warranty | 1-year parts, labor and travel |
Source: Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet
All Agilent 6410 Triple Quadrupole documents by type
How to use the product for one specific task, with worked examples.
- Agilent 6410 Triple Quadrupole LC/MS System Application Note: Quantification of Lovastatin in Human Plasma 8 p
- Agilent High-Throughput Protein Quantitation Using MRM Application Note 8 p
- Agilent 6410 Triple Quadrupole Mass Spectrometer Application Brief: Quantitative Analysis of Perfluorooctanoic Acid by L 4 p
- Agilent 6410 Triple Quadrupole Analysis of Nitrofuran Metabolites Application Note 6 p
Questions answered in these manuals
What is the throughput of the RF-MS system?
The system analyzes over 3,500 samples per instrument per shift.
From: Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet
Does the system require sample extraction?
No, on-line clean-up permits direct sampling from assay plates containing microsomal protein without pre-processing.
From: Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet
What is the concentration range for lovastatin quantification?
The method covers a wide range of 0.1 ppb to 50 ppb of lovastatin in human plasma.
What is the runtime for the analysis?
The method achieves a short runtime of approximately 1.2 minutes.
What software is used for dynamic MRM acquisition?
MassHunter acquisition software equipped with dynamic MRM functionality is used to monitor the transition list.
From: Agilent High-Throughput Protein Quantitation Using MRM Application Note
Which software is used for statistical analysis of MRM results?
Mass Profiler Pro is used to perform principal component analysis, hierarchical clustering, and ANOVA analysis.
From: Agilent High-Throughput Protein Quantitation Using MRM Application Note