Agilent 6410 Triple Quadrupole Mass Spectrometer Manuals

ManualLib has 4 documents for the Agilent 6410 Triple Quadrupole Mass Spectrometer: 1 product leaflet, 3 application notes. Every file can be read online or downloaded as a PDF for free.

Product Leaflet 1Application Note 3

Key facts

Brand
Agilent
Model
6410 Triple Quadrupole Mass Spectrometer
Documents
4
Languages
EN
Last added
2012-07-04

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Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet

Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet

Product Leaflet 2 pages · 159 KB · EN

The Agilent 6410 triple quadrupole mass spectrometer combined with BioTrove's RapidFire system provides an integrated solution for high-throughput preparation and analysis of in vitro biological assays in pharmaceutical drug research. This native detection technology allows researchers to obtain mass spectrometry-based data in a fraction of the time needed for traditional LC-MS techniques, specifically for screening Cytochrome P450 (CYP) interactions.

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Agilent 6410 Triple Quadrupole Mass Spectrometer specifications

Sample ThroughputOver 3,500 samples/instrument/shift
Plate FormatSBS standard 96 or 384-well plates
Sample ProcessingOn-line clean-up permits direct sampling
Ionization ModesESI, APCI and multimode
Weight170 kg (875 lbs)
Footprint152 x 183 x 76 cm (WxHxD)
Electrical Requirements115 V, 60 Hz, 15 AMP
Warranty1-year parts, labor and travel

Source: Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet

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Questions answered in these manuals

What is the throughput of the RF-MS system?

The system analyzes over 3,500 samples per instrument per shift.

From: Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet

Does the system require sample extraction?

No, on-line clean-up permits direct sampling from assay plates containing microsomal protein without pre-processing.

From: Agilent 6410 Triple Quadrupole Mass Spectrometer with BioTrove RapidFire System Product Leaflet

What is the limit of quantitation for this method?

The limits of quantitation were achieved at 50 pg/mg.

From: Agilent 6410 MS Application Note: Determination of Cocaine and Metabolites in Hair

Which drugs are analyzed in this procedure?

The method analyzes cocaine, benzoylecgonine, cocaethylene, and norcocaine.

From: Agilent 6410 MS Application Note: Determination of Cocaine and Metabolites in Hair

What equipment is used for the CYP450 inhibition assay?

The system uses an Agilent 6410 triple quadrupole mass spectrometer interfaced with a BioTrove RapidFire RF-MS inlet system.

From: Agilent 6410 Triple Quadrupole Mass Spectrometer CYP450 Inhibition Application Note

What software is used for data acquisition and analysis?

Data acquisition uses Agilent MassHunter workstation software, while final data analysis is performed using BioTrove RapidFire integrator software.

From: Agilent 6410 Triple Quadrupole Mass Spectrometer CYP450 Inhibition Application Note