Key facts
Start here

Agilent 6460 Triple Quadrupole LC/MS Data Sheet
This document provides a data sheet for the Agilent 6460 Triple Quadrupole LC/MS system. It highlights key performance metrics such as MS/MS sensitivity of 1 pg of reserpine injected on column with a signal-to-noise ratio greater than 1000:1 when using Agilent Jet Stream technology.
Read onlineAgilent 6460 Triple Quadrupole specifications
| MS/MS Sensitivity (ESI) | 1 pg of reserpine injected on column, with Agilent Jet Stream technology, quantifying on the transition m/z 609 to 195 |
|---|---|
| Signal-to-noise ratio | >1000:1 |
| Mass range | m/z 5-3,000 |
| Polarity switching time | 100 ms |
| Mass resolution settings (FWHM) | 0.7 u; Wide: 1.2 u; Widest: 2.5 u |
| Mass accuracy (5-1,000 m/z) | 0.1 Da |
| Dynamic range | >6.0 x 10^9 |
| Scan rate | 5,200 u/s |
All Agilent 6460 Triple Quadrupole documents by type
Ratings, dimensions and ordering codes, for selection and design work.
How to use the product for one specific task, with worked examples.
- Agilent 6460 Triple Quadrupole LC/MS Determination of Acidic Herbicides Application Note 8 p
- Agilent Quantification of Alprazolam in Dried Blood Spots Using Agilent 1290 Infinity LC System and 6460 Triple Quadrupo 2 p
- Agilent LC/MS/MS quantitation of β-estradiol 17-acetate using an Agilent 6460 Triple Quadrupole LC/MS working in ESI negative ion mode Application Note 8 p
- Agilent 6460 Triple Quadrupole LC/MS Application Note for PFCA/PFSA Detection 8 p
- Agilent 6460 Triple Quadrupole LC/MS Pesticide Analysis Application Note 8 p
- Agilent 6460 Triple Quadrupole LC/MS System with 1290 Infinity LC Application Note 8 p
- Agilent 6460 Triple Quadrupole LC/MS System Application Note 4 p
- Agilent SAMHSA-Compliant LC/MS/MS Analysis of Benzoylecgonine in Urine with Agilent Bond Elut Plexa PCX Agilent Poroshell 120 Manual 6 p
- Agilent 6460 Triple Quadrupole LC/MS Application Note 8 p
Questions answered in these manuals
What is the MS/MS sensitivity of the Agilent 6460 with Jet Stream technology?
The system achieves a signal-to-noise ratio greater than 1000:1 when quantifying on the transition m/z 609 to 195.
What are the available mass resolution settings?
The instrument offers three FWHM settings: 0.7 u, Wide at 1.2 u, and Widest at 2.5 u.
What technology enables ultra-sensitive performance for the Agilent 6460?
The system is equipped with Agilent Jet Stream Technology to provide ultra-sensitive performance for analytes in complex matrices.
From: Agilent 6460 Triple Quadrupole LC/MS System Product Brochure
What are the key applications of the 6460 system?
The instrument is ideal for environmental and food safety analysis, clinical research, and peptide quantitation.
From: Agilent 6460 Triple Quadrupole LC/MS System Product Brochure
Does this method require solid phase extraction?
No, the analysis is performed by direct aqueous injection, negating the need for solid phase extraction.
From: Agilent 6460 Triple Quadrupole LC/MS Determination of Acidic Herbicides Application Note
What are the limits of detection for the compounds?
Limits of detection were less than 10 ng/L (10 ppt) for all the compounds in the suite.
From: Agilent 6460 Triple Quadrupole LC/MS Determination of Acidic Herbicides Application Note
