This application note describes the use of an Agilent 6460 triple quadrupole LC/MS equipped with Agilent Jet Stream technology and direct aqueous injection for the analysis of a suite of acidic herbicides in several water matrices, thereby negating the need for solid phase extraction. Standard deviations in the range of 2.5% to 6.6% for analyte precision and recoveries of between 91.5% and 105.1% were observed over 11 batches of samples. Limits of detection were less than 10 ng/L (10 ppt) for all the compounds in the suite thus meeting current industry standards.
The document presents an analytical method for detecting a suite of acidic herbicides in potable and environmental water samples. The method utilizes direct aqueous injection, eliminating the need for time-consuming solid phase extraction (SPE) steps typically required for these compounds.
Validation was performed on 11 batches of samples including borehole groundwater, potable water, river water, and deionized water. The results demonstrated recoveries between 91.5% and 105.1%, standard deviations ranging from 2.5% to 6.6%, and limits of detection less than 10 ng/L (10 ppt) for all compounds in the suite.
| Column dimensions | 2.1 mm x 100 mm |
|---|---|
| Column temperature | 60 °C |
| Total run time | 26.0 min |
| Gas temperature (Negative) | 250 °C |
| Veap voltage (Negative) | 2000 V |
No, the analysis is performed by direct aqueous injection, negating the need for solid phase extraction.
Limits of detection were less than 10 ng/L (10 ppt) for all the compounds in the suite.
Recoveries ranged between 91.5% and 105.1% over 11 batches of samples.