Agilent 6540 Accurate-Mass Q-TOF Manuals

ManualLib has 2 documents for the Agilent 6540 Accurate-Mass Q-TOF: 1 other, 1 application note. Every file can be read online or downloaded as a PDF for free.

Other 1Application Note 1

Key facts

Brand
Agilent
Model
6540 Accurate-Mass Q-TOF
Documents
2
Languages
EN
Last added
2012-07-05

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Agilent 6540 Accurate-Mass Q-TOF Technical Overview

Agilent 6540 Accurate-Mass Q-TOF Technical Overview

Other 8 pages · 178 KB · EN

The document presents a technical overview demonstrating how the Agilent 6540 Accurate-Mass Q-TOF LC/MS System can perform metabolic stability, profiling, and identification in a single experiment. This approach maximizes information obtained from one analysis compared to using separate methods for quantitation and identification.

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Agilent 6540 Accurate-Mass Q-TOF specifications

Drying Gas Temperature350°C
Sheath Gas Flow12 L/min
Capillary Voltage4000 V
Mass Range (MS and MS/MS)100-1000 m/z
Acquisition Rate (Combined Mode)5 spectra/sec
Collision Energy28 eV

Source: Agilent 6540 Accurate-Mass Q-TOF Technical Overview

All Agilent 6540 Accurate-Mass Q-TOF documents by type

Application Note 1

How to use the product for one specific task, with worked examples.

Questions answered in these manuals

What modes does the Agilent 6540 operate in for this study?

The system was operated in an initial MS-only mode at 5 Hz acquisition rate and an automatic MS/MS mode with expected metabolites on the inclusion list.

From: Agilent 6540 Accurate-Mass Q-TOF Technical Overview

How does the Agilent 6540 compare to the Triple Quadrupole system?

The quantitative data obtained using the 6540 QTOF showed good correlation with analysis performed on the Agilent 6460 Triple Quadrupole LC/MS System.

From: Agilent 6540 Accurate-Mass Q-TOF Technical Overview

What is the mass error in MS mode for the example compound?

The mass error was only 0.33 ppm.

From: Agilent 6540 Accurate-Mass Q-TOF Application Note

What is the MS/MS mass accuracy above m/z 100?

The MS/MS mass accuracy is better than 2 ppm.

From: Agilent 6540 Accurate-Mass Q-TOF Application Note