The Agilent 6460 Triple Quadrupole LC/MS with Agilent Jet Stream Technology achieves sensitivity and resolution specifications after autotune without manual user intervention. The instrument provides a range of features, including MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM.
This document provides a data sheet for the Agilent 6460 Triple Quadrupole LC/MS system. It highlights key performance metrics such as MS/MS sensitivity of 1 pg of reserpine injected on column with a signal-to-noise ratio greater than 1000:1 when using Agilent Jet Stream technology.
| MS/MS Sensitivity (ESI) | 1 pg of reserpine injected on column, with Agilent Jet Stream technology, quantifying on the transition m/z 609 to 195 |
|---|---|
| Signal-to-noise ratio | >1000:1 |
| Mass range | m/z 5-3,000 |
| Polarity switching time | 100 ms |
| Mass resolution settings (FWHM) | 0.7 u; Wide: 1.2 u; Widest: 2.5 u |
| Mass accuracy (5-1,000 m/z) | 0.1 Da |
| Dynamic range | >6.0 x 10^9 |
| Scan rate | 5,200 u/s |
The system achieves a signal-to-noise ratio greater than 1000:1 when quantifying on the transition m/z 609 to 195.
The instrument offers three FWHM settings: 0.7 u, Wide at 1.2 u, and Widest at 2.5 u.
Supported modes include MS, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan, precursor ion scan, and SIM.