Agilent G6410AA Manuals

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Application Note 4

Key facts

Brand
Agilent
Model
G6410AA
Documents
4
Languages
EN
Last added
2012-07-02

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Agilent G6410AA Triple Quadrupole Mass Spectrometer Application Note

Agilent G6410AA Triple Quadrupole Mass Spectrometer Application Note

Application Note 8 pages · 1 MB · EN

This document presents a fast, sensitive, and reproducible technique for confirming the presence of drugs of abuse (DOA) in oral fluids (OF) using the Agilent G6410AA Triple Quadrupole Mass Spectrometer. The method utilizes liquid chromatography/tandem mass spectrometry (LC/MS/MS) with a 1.8-µm, C18 column to achieve high chromatographic resolution with elution times of less than 4.2 minutes for THC and less than 1.5 minutes for other analyzed drugs. The technique meets the sensitivity requirements set by the United States Substance Abuse and Mental Health Services Administration (SAMHSA) for workplace testing.

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Agilent G6410AA specifications

Column temperature40°C
Flow rate0.5 mL/min
Elution time (THC)Less than 4.2 minutes
Elution time (Cocaine, Amphetamine, Methamphetamine, MDMA)Less than 1.5 minutes

Source: Agilent G6410AA Triple Quadrupole Mass Spectrometer Application Note

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Questions answered in these manuals

What is the elution time for THC in this method?

The elution time for THC is less than 4.2 minutes.

From: Agilent G6410AA Triple Quadrupole Mass Spectrometer Application Note

What is the elution time for cocaine, amphetamine, methamphetamine, and MDMA?

The elution time for these drugs is less than 1.5 minutes.

From: Agilent G6410AA Triple Quadrupole Mass Spectrometer Application Note

Which aflatoxins are determined in this method?

The method determines aflatoxin G1, G2, B1, and B2 residues in cereals.

From: Agilent G6410AA LC/MS/MS Aflatoxin Determination Application Note

What is the limit of detection for the aflatoxins?

The limits of detection for all aflatoxins were less than 1 ng/mL in cereals.

From: Agilent G6410AA LC/MS/MS Aflatoxin Determination Application Note

What is the minimum detection limit for chloramphenicol in honey, shrimp, and chicken using this method?

The method provides a limit of detection at 10 ppt in the sample matrix.

From: Agilent G6410AA LC/MS Application Note: Chloramphenicol Analysis in Food

What is the maximum flow rate used for the HPLC system in this analysis?

The flow rate for the HPLC system is set to 0.4 mL/min.

From: Agilent G6410AA LC/MS Application Note: Chloramphenicol Analysis in Food