Agilent 920-LC Manuals

The Varian 920-LC analytical high performance liquid chromatograph is an integrated, pre-configured, pre-plumbed system that can be controlled by Varian Galaxie™ Chromatography Software on a single computer, or through a fully networked client and acquisition server. The low pressure quaternary gradient reciprocating dual piston pump with built-in Degasser, or isocratic pump delivers consistent, reliable solvent flow throughout the HPLC system. The autosampler direct injection method ensures carryover of less than 0.01% and has optional sample cooling. A column heater holds up to two columns from 4.6 to 13 mm ID and 50 to 300 mm length. Options of a UV-Vis or photodiode array (PDA) detector provide high sensitivity and low noise. Fluorescence, refractive index (RI) and evaporative light scattering (ELS) detectors with a cooling option can also be added for the analysis of non UV-Vis absorbing compounds.

This article presents a method for the USP assay of ibuprofen oral suspension using Varian 920-LC and Pursuit™ XRs C8 column. The results obtained from the experiment show that all performance requirements of the USP methods are satisfied and demonstrate a significant enhancement in laboratory productivity when using this system.

This article describes a HPLC analysis method for the USP assay of ibuprofen and the limit test of ibuprofen-related compound C in ibuprofen tablets using Varian 920-LC liquid chromatograph and Varian Pursuit C18 column. The experimental results show that this method has high sensitivity and selectivity and can be used for rapid analysis of ibuprofen-related compound C.

Describes a method for the analysis of polycyclic aromatic hydrocarbons (PAHs) using the Varian 920-LC and Pursuit™ 3 PAH Column