Agilent Manuals

This document describes the analysis method for sulfur components in various LPGs. A highly selective pulsed flame photometric detector is used, and a dual-channel configuration is employed for the analysis. This method allows for the analysis of all components of interest in one run.

This article describes a method for quantitative measurement of the cardiac glycoside, Digoxin, in human plasma using a Varian 1200L LC/MS/MS system in the negative ion detection mode. This method is capable of detecting Digoxin levels as low as 15 picograms.

This application note introduces a new method for studying the dynamics of biomolecules, based on ultrafast NMR spectroscopy and the performance of Varian cold probes.

This is an application note that introduces the application of mass spectrometry with evaporative light scattering detection

This publication describes the method of controlling Agilent 1260 Infinity LC Systems using Waters Empower chromatography data software through emulation mode. The software supports the evaluation of two-dimensional, three-dimensional, and spectral raw data acquired by Agilent 1260 Infinity UV detectors, except the Agilent 1260 Infinity DAD. It also provides support for maintenance and diagnostics through Agilent Lab Monitor and Diagnostic software.

The document evaluates the usefulness and performance of the Varian 1200L LC/MS/MS for the analysis of Cyclosporin A. The system includes automated on-line extraction and is controlled and fully automated through the Varian MS Workstation software. The Multi Reaction Monitoring (MRM) capability is used to demonstrate the sensitivity and robustness of the LC/MS/MS system.

This application note describes a method for characterizing the multi-component, polymeric emulsifier Ethomeen T/20H using TurboDDS™ on the Varian 500-MS Ion Trap LC/MS

The Varian 500-MS Ion Trap Mass Spectrometer can be used for the analysis of isocyanate derivatives. This method separates and identifies four isocyanate derivatives at low concentrations, with a short analysis time.

This article describes the sensitive impurity detection of drug intermediates produced by Agilent Technologies, Inc. High purity standards are required for drug intermediates in the production of flurazepam, enalapril, and flunarizine. The Agilent LC/MSD Ion Trap was used to obtain LC/MS and MS/MS data for each intermediate, providing sufficient information to propose structures for the corresponding impurities.

This document introduces a method for pesticide analysis using an Agilent J&W DB-35ms UI 20 m × 0.18 mm, 0.18 µm column, which can effectively separate organochlorine and organophosphorus pesticides with good separation and reproducibility.

This study evaluated the performance of the Agilent 1260 Infinity Analytical SFC system for the analysis of thiourea in two model compounds. The results showed excellent linearity, repeatability, and limits of detection.

This method is applicable to a wide range of animal and plant tissues including dairy products, grains, fruit and vegetables and oil seeds such as poppy seeds. It is suitable for cadmium concentration in the range 0.01-0.3 µg/g. Sample is digested by wet ashing and cadmium is then complexed and extracted into an organic solvent. After removal of the spent aqueous phase the organo metallic complex is destroyed by the addition of dilute HNO3. This aqueous phase containing the stripped cadmium is then analyzed by Graphite Furnace Atomic Absorption Spectroscopy (GFAAS). The additional stripping step is employed to improve precision and facilitate the use of aqueous standards.

The document describes the determination of Cd, Cr, Cu, Ni, and Pb in a concentrated CaCl2/NaCl solution using AAS. The analysis of such a high solids containing solution presents challenges, which are addressed through indirect flame atomization, direct flame atomization, and graphite furnace atomization methods. It is important to clean the nebulizer and measure a reagent blank during the analysis. The results are compared against a calibration graph. The document provides calibration data for Cd.