Agilent Manuals

This document describes the separation performance of ZORBAX XDB-C8 for Procainamides and metabolites at a pH of 7.0 or higher. It provides good peak shape and resolution, making it suitable for pharmaceutical applications.

This document describes a method for separating local anesthetics on different bonded-phase ZORBAX columns and analyzes the selectivity of the separations.

This document describes that Agilent Technologies' Rx-Silica highlights good peak shape of basic compounds in opiate drugs. These basic compounds have poor peak shape on many reversed-phase columns. ZORBAX Rx-SIL has an extremely homogeneous silica surface with uniform associated silanols and low acidity. ZORBAX Rx and StableBond columns show significantly reduced band tailing and improved column efficiency when analyzing basic compounds.

This document describes the features of ZORBAX StableBond C8, which has a sterically protected bonded phase that allows stable operation at low mobile-phase pH. ZORBAX SB-C8 separates basic compounds with good resolution and peak shape using simple mobile phases. The document also provides the conditions for using ZORBAX Rx/SB-C8 in pharmaceutical applications.

The document introduces a stable C18 column that can be used for high temperature separation of low molecular weight polymers

This document describes a method for rapid quality testing of uncured epoxy resins. The method utilizes HPSEC instrument with the following conditions: column: DuPont HPLC ZORBAX PSM 60S, 6.2 mm x 25 cm (Agilent P/N: 880957-802); mobile phase: tetrahydrofuran; flow rate: 1.5 mL/min; temperature: 22°C; detector: UV Abs (254 nm); sample: Epon 836.

The document describes the features and characteristics of commercial polyethylene, including the requirement of elevated temperature and aggressive solvent systems for high-performance size exclusion chromatography (HPSEC). It also highlights the stability of ZORBAX PSM size exclusion columns with aggressive solvent systems. The document provides detailed analysis conditions and information about the application in polymers. It is authored by Robert Ricker, an application chemist at Agilent Technologies.

This document describes how to use high-performance liquid chromatography (HPSEC) to monitor differences in synthetic polymer production. Specifically, the material uses the ZORBAX Bimodal S column (Agilent P/N: 880957-814) to perform size exclusion separations and uses ultraviolet detection (UV 254 nm) to detect the quality of polymethacrylate materials.

This document introduces a method for analyzing highly hydrophilic compounds using the Agilent ZORBAX Rx-SIL column and a reversed-phase mobile phase. This method can effectively separate urea and uracil, which are both unretained by reversed-phase columns because they are highly hydrophilic.

The analysis of organic acids is important for both the food and cosmetic industries. Organic acids are naturally found in a wide variety of food products, fruits, and corresponding beverages. They are also used in the cosmetic industry as dermatological agents. Agilent ZORBAX StableBond columns are highly stable at low pH, including the use of mobile phases containing 0.1% trifluoroacetic acid at pH 2.1. ZORBAX StableBond columns provide good peak shapes for acidic compounds.

This document describes the separation of a series of substituted anilines.

This document introduces the method of separating basic compounds using Agilent ZORBAX Stablebond column, including column conditions, pH effect on separation selectivity.

This document describes the performance comparison of the non-endcapped Agilent ZORBAX SB-C18 column and its doubly endcapped counterpart in the separation of fat-soluble vitamins.

This Application Note describes four separation strategies for purifying compounds from non-baseline separated peaks.