Agilent Manuals

An Agilent 1290 Infinity LC System is optimized for the lowest possible extra-column volume, to ensure minimal band broadening and optimal results from a small dimension, Agilent ZORBAX RRHD Eclipse Plus C18, 2.1 × 50 mm, 1.8 µm column. Improvements to isocratic and gradient analyses are evident, with the early eluting peaks from the isocratic analysis showing the greatest improvement of up to a 58% increase in efficiency (k’ = 1.6). Gradient analyses are improved by 24 to 32% with respect to conditional peak capacity (k’ = 1.3 to 5.3). Additionally, there is no strong correlation between flow rate and the effect of extra-column volume, with respect to column performance for isocratic and gradient analyses.

This document introduces how to detect synthetic cannabinoids in oral fluid

This application note introduces a method to enable DBS analysis of basic drugs on Agilent Bond Elut Dried Matrix Spotting (DMS) cards, which is achieved by optimizing desorption conditions.

A method has been developed on the Agilent 7000 GC Triple Quadrupole GC/MS/MS system for the analysis of foods for 20 chemicals that may be present in printing inks applied to the external surface of cartonboard packaging material. These substances may diffuse through the cartonboard or set-off onto the food contact surface and then migrate into food. The method described is suitable for the reliable determination of ink substances in packed foods at single-figure parts-per-billion (ppb, µg/kg) levels.

This document describes a multi-residue analysis using an Agilent J&W FactorFour VF-35ms column for PAHs, PCBs, and OCPs. PAHs are compounds with two or more aromatic rings formed during incomplete combustion or pyrolysis of organic matter. OCPs are pesticides containing carbon, hydrogen, and chlorine atoms that break down slowly, persist in the environment, and bioaccumulate in organisms. PCBs are characterized by two phenyl groups with varying numbers of chlorine atoms and are used in various industrial and commercial applications. The method allows for the analysis of 16 EPA PAHs, 17 PCBs (including 6 EU marker PCBs), and 24 common OCPs in a single run at different concentration levels.

This application note demonstrates the performance of the Select PAH GC column for multi-residue analysis

This application note provides detailed instructions on how to use the Stratagene Mx3000P QPCR system to detect and quantify various agricultural and economically important fungi.

This Application Note describes the transfer of a United States Pharmacopeia (USP) method for prednisolone from normal phase HPLC to SFC using the Agilent 1260 Infinity Hybrid SFC/UHPLC System. The results show that the SFC method meets the system suitability criteria, is 4x faster, and results in 17x lower solvent expenses. Robustness tests on the SFC method demonstrate excellent robustness for routine analysis.

The document introduces a novel dried matrix adsorbent for extracting acidic drugs from blood samples. By optimizing the desorption conditions, the adsorbent can enhance the sensitivity of detecting acidic drugs.

This application note describes a method for detecting residual CHO host cell DNA using the Agilent Mx3005P QPCR System. The method uses sequence-specific primers and probe to detect CHO host cell DNA, producing more specific, sensitive, and faster results than conventional methods such as blot hybridization.

This document describes the GC analysis of total fatty acid methyl esters (FAME) and methyl linolenate in biodiesel using the revised EN14103:2011 method. Four different types of biodiesel samples were manually prepared and analyzed, and the total FAME and methyl linolenate contents were determined with precision exceeding the method’s specifications.

This compendium describes Agilent materials analysis instruments applications in Polymers and Rubbers