Agilent Manuals

This document describes the application of Agilent RapidFire/MS systems for high-throughput in vitro ADME analysis. Permeability assays such as Caco-2 and PAMPA are used to mimic the absorption of potential drug candidates by human intestinal cells. The Agilent RapidFire High-throughput Mass Spectrometry System, coupled with QQQ or TOF MS, enables rapid sample processing and provides results comparable to traditional LC/MS methods in a fraction of the time, making it a cost-effective and highly productive method for assessing permeability in the drug discovery process.

This document introduces the solutions provided by Agilent Technologies in the food and agriculture field, including products, applications, software and services

Agilent Technologies provided an application compendium that introduces detailed methods for the analysis of rubbers by GPC/SEC, including natural rubber, synthetic rubber, polydimethyl siloxane, etc.

This document describes a method for analyzing antibiotics in meat using an Agilent Poroshell 120 EC-C18 column. The method uses a gradient method and UV detection, and it can be quickly optimized.

This document introduces the application of Agilent RapidFire/MS systems for high-throughput in vitro ADME analysis, with a focus on cytochrome P450 (CYP) inhibition. The system combines high-throughput sample processing with triple quadrupole (QQQ) or time-of-flight (TOF) mass spectrometry (MS) to streamline ADME assay analysis.

This document introduces the application of Agilent RapidFire/MS systems for high-throughput in vitro ADME analysis. The authors emphasize the importance of analyzing cytochrome P450 (CYP) inhibition and the need to evaluate a larger number of samples. They propose a fast, efficient, and cost-effective method for analysis.

This document describes the method of high performance DNA oligonucleotide purification using Agilent TOP-DNA. Synthetic oligonucleotides have become readily available due to solid phase synthesis, but there are some limitations such as the need for high coupling yields and difficulties in purification. Agilent has developed a purification method specifically designed for DNA oligomers up to 150 bases.

This data sheet provides detailed information about the Agilent AMMP-6220 6-20 GHz low noise amplifier, including product features, applications, and description.

This document introduces the Agilent TOP-RNA high-performance RNA oligonucleotide purification technology

This study demonstrates the use of Agilent’s new MS/MS spectral metabolomics library to elucidate the identification of several amino acids that are important in malaria metabolism.

This document describes how a pharmaceutical company maximizes efficiency in early drug discovery by using Agilent Analytical Studio Reviewer (ASR) for high-throughput LC/MS analyses to determine the correct compounds. The company is one of the largest pharmaceutical companies in Japan, with a focus on developing drugs in the therapeutic categories of urology, immunology and infectious diseases, oncology, neuroscience, diabetes mellitus complications, and metabolic diseases.

This application note describes an improved microextraction method for sample preparation that can be used to analyze a variety of therapeutic categories of pharmaceuticals on an Agilent Poroshell 120 column. The method is simple, fast, economical, and effective for therapeutic drug monitoring and forensic chemistry.

This document describes the method of fast refinery gas analysis using the Agilent 490 Micro GC QUAD. The authors demonstrate the analysis results obtained in about two minutes through experimental results. The document also introduces the features of the equipment and the materials used.