This document describes the performance of Agilent ZORBAX Bonus-RP column, which has superior column efficiency and peak shape, and can be used for the determination of ulcer-treatment drugs
This document presents an application note by Robert Ricker regarding the separation of ulcer-treatment drugs using Agilent ZORBAX Bonus-RP columns. The text explains that at intermediate pH, these basic drugs elute with reduced peak tailing compared to conventional alkyl C8 columns. The superior performance is attributed to the column's construction, which combines ultrapure Type B silica support with a stationary phase featuring an amide group, bulky diisobutyl groups, and dense endcapping.
| Column Dimensions | 4.6 x 150 mm |
|---|---|
| Part Number | 883668-901 |
| Mobile Phase Composition | Na citrate, 20 mM, pH 6.1: MeOH, (80:20) |
| Detector Wavelength | 220 nm |
| Flow Rate | 1mL/ min |
The document specifies a column dimension of 4.6 x 150 mm.
The stated flow rate is 1 mL/min.