This document describes the high reproducibility of the Agilent ZORBAX Rx-C8 column in the detection of basic drugs and introduces the strict quality control in the production process of the column.
The document presents an application demonstrating the consistency of elution patterns for basic drugs, specifically amphetamines, when analyzed on Agilent ZORBAX Rx and StableBond columns. The study compares results from two different manufacturing lots (A90C6 and B92C6) to verify quality control.
The procedure specifies a flow rate of 2 mL/min.
The column is operated at a temperature of 40°C.
Detection is performed at a wavelength of 254 nm.