This document introduces the method for determining As in samples containing high concentration of chloride using Agilent 4500 ICP-MS.
This document addresses the spectral interference of ArCl on Arsenic (As) determination in samples containing high levels of chloride. It explains that while high-resolution mass spectrometry can separate these ions, it compromises detection limits. The 4500 ICP-MS overcomes this by using mathematical correction via elemental equations resident in the ChemStation software.
| Resolving power required for separation | >7500 |
|---|---|
| Ion signal stability | <1%RSD over 2 hours |
| Spray chamber temperature control | +/-0.1 °C |
| RF power | 13kW |
| Sampling depth | 8 mm |
| Plasma gas flow | 16 l/min |
| Auxiliary gas flow | 1.0 Vmin |
| Carrier gas flow | 21.15 Vmin |
| Nebulizer type | Concentric type |
It uses elemental equations resident in the ChemStation software to correct for interferences on both As and Se simultaneously.
Yes, it can determine As at the ppb and sub-ppb level even in 5% HCl using interference correction.
The document demonstrates determination from 0 to 200 µg/l.