This Application Note describes how to use the Agilent 7700x ICP-MS with ISIS Discrete Sampling to perform high-throughput analysis of high-matrix samples. Using ISIS-DS, difficult, high-matrix analyses can be performed in a fraction of the time typically required, with no compromise in analytical performance.
The document describes a method to maximize productivity when analyzing difficult, high-matrix environmental samples such as soils and sludges. By combining helium collision cell mode, aerosol dilution using the High Matrix Introduction (HMI) system, and ISIS Discrete Sampling (ISIS-DS), the Agilent 7700x ICP-MS can perform robust analyses in a fraction of the time typically required.
The system performs a run-to-run analysis in 1.99 minutes per sample.
A total of 275 analyses were performed in 8 hours, 8 minutes.
Internal standard recoveries must exceed 70% of the ISTD response in the calibration blank.