Increased productivity by quick identification of samples that fail regulatory requirements using the Agilent 6140 single quadrupole LC/MS system and Analytical Studio Browser software
This document details a method for the high-throughput screening of phthalates in toys and childcare articles to ensure compliance with regulatory limits. The method utilizes the Agilent 6140 single quadrupole LC/MS system coupled with an Agilent 1200 Series Rapid Resolution LC system. By using sub-2 µm columns and overlapped injections, the analysis run time is reduced to less than one minute per sample, significantly increasing productivity for consumer product testing agencies.
| Run Time | 0.5 minutes |
|---|---|
| Flow Rate | 0.6 mL/minutes |
| Injection Volume | 2 µL |
| Dry gas temperature | 250 °C |
| Capillary voltage | 4000 V |
| Ionization Mode | ESI Positive mode |
The method achieves a run time of less than 1 minute, specifically 0.5 minutes for the isocratic run.
Agilent Analytical Studio Browser (ASB) is used to quickly identify samples that exceed regulatory requirements.
The method uses Agilent ZORBAX Eclipse Plus RRHT 1.8 µm columns.