This Application Note describes a fast quality control method for the analysis of notoginsenoside R1 and Ginsenosides Rg1, Re and Rb1 using the Agilent 1290 Infinity LC system and an Agilent ZORBAX RRHD 1.8 µm column. Compared to conventional methods, the rapid method is much faster, and maintains the same performance and quality of separation. In addition, solvent consumption is also dramatically reduced.
This document presents an optimized liquid chromatography (LC) method for the analysis of Notoginsenoside R1 and Ginsenosides Rg1, Re, and Rb1 in Compound Traditional Chinese Medicine (TCM). The method utilizes the Agilent 1290 Infinity LC system combined with an Agilent ZORBAX RRHD 1.8 µm column to significantly reduce analysis time compared to conventional HPLC methods.
The analysis was completed in 12.6 minutes.
The condition specifies a flow rate of 0.4 mL/min.
The column temperature is set to 20.00 °C.