Agilent 500 Ion Trap LC/MS Application Note: Determination of Opiates and Other Drugs of Abuse

This document describes a method for the rapid, sensitive and reproducible detection of seven common drugs of abuse using the Agilent 500 Ion Trap LC/MS.

Brand: Agilent
Document type: Application Note
Language: English
Pages: 4
File format: PDF
File size: 98 KB
Published: 11 June, 2012
Updated: 30 September, 2023
Models: 500 Ion Trap LC, 500 Ion Trap
MD5 checksum: 8DFD56DFE371CE27CB793B01ED327B65
PDF: Agilent 500 Ion Trap LC/MS Application Note: Determination of Opiates and Other Drugs of Abuse PDF

About this manual

This document presents a validated analytical method for the determination of opiates and other drugs of abuse. The study utilizes the Agilent 500 Ion Trap LC/MS system equipped with an ESI source to separate, detect, identify, and quantify seven specific analytes: codeine, oxycodone, hydrocodone, meperidine, cocaine, methadone, and THC.

What's inside

Abstract
Introduction
Instrumentation
Materials and Reagents
HPLC conditions
MS parameters
Results and Discussion
Conclusion

Frequently asked questions

Which seven drugs of abuse are analyzed in this method?

The method analyzes codeine, oxycodone, hydrocodone, meperidine, cocaine, methadone, and THC.

What is the linear range for calibration curves?

Calibration curves were found to be linear from 5 to 500 ppb.

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