Agilent 1260 Infinity Quaternary and Binary Pumps Technical Overview

Describes the working principle and performance of two gradient pumps in the Agilent 1260 Infinity LC series, which are the quaternary low pressure mixing pump and the binary high pressure mixing pump.


Agilent 1260 Infinity Quaternary and Binary Pumps Technical Overview - cover page
Brand
Agilent
Category
Other
Document type
Application Note
Language
English
Pages
12
File format
PDF
File size
860 KB
Published
05 July, 2012
Updated
30 September, 2023
MD5 checksum
4865A9D95563CA2A2842F97D186B51FF

About this manual

This document provides a technical overview comparing the Agilent 1260 Infinity Quaternary Pump and the Agilent 1260 Infinity Binary Pump. Both pumps are part of the Agilent 1260 Infinity LC family and are designed for analytical scale liquid chromatography gradient runs. The text details their specific application ranges, noting that the Quaternary pump is optimized for 5% to 95% organic gradients, while the Binary pump excels from 0% to 100% organic, particularly for low or high organic percentages and when using TFA as a modifier.

What's inside

  • Scope of low and high pressure mixing
  • Retention time precision
  • Flow precision and mixing performance
  • Compressibility settings
  • Stroke volumes
  • Experimental conditions
  • Results and discussion
  • Low organic percentage performance
  • High organic percentage performance
  • TFA modifier performance

Specifications

Quaternary Pump Flow Rate Range0.3 up to 10 mL/min
Binary Pump Flow Rate Range0.05 to 5 mL/min
Quaternary Pump Optimum Gradient Range5% to 95% organic
Binary Pump Optimum Gradient Range0% to 100% organic
Quaternary Pump Flow Precision< 0.07% RSD
Binary Pump Flow Precision< 0.07% RSD
Quaternary Pump Composition Precision< 0.2% RSD
Binary Pump Composition Precision< 0.15% RSD

Frequently asked questions

What is the optimum gradient range for the Agilent 1260 Infinity Quaternary Pump?

The optimum gradient range is between 5% to 95% organic.

When is the Agilent 1260 Infinity Binary Pump the best choice?

It is the best choice for gradients from 0% to 10%, 90% to 100%, and when using TFA as a modifier.

What is the practical flow rate range for the Agilent 1260 Infinity Binary Pump?

The practical flow rate range is from 0.05 to 5 mL/min.

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