This document introduces a technical overview of a method for fast GC analysis using large volume injection and rapid mass spectrometry, which can significantly reduce analysis time, improve sensitivity and lower detection limit
This document provides a technical overview of the Fast High Throughput GC analysis method for pesticides. It highlights how combining large volume injection with rapid mass spectroscopy using an Agilent Rapid-MS column reduces analysis length by up to five times compared to traditional approaches while increasing sensitivity and lowering detection limits.
The text details specific operating conditions, including the use of a VF Rapid-MS pesticide column (part number CP8138) with a 2.5 m x 0.53 mm retention gap and an Agilent 240-MS detector. It lists chromatographic parameters such as oven temperatures, injection volumes, and provides a table identifying specific pesticide peaks by retention time.
| Column ID | 0.53 mm |
|---|---|
| Retention Gap Size | 2.5 mx 0.53 mm |
| Injection Volume | 50 uL |
| Sample Concentration | 0.8 ppb |
| Injector Temperature Program | 65 °C (0.50 min) — 200 °C/min — 350 °C (5 min) |
| Column Oven Program | 40 °C (3.00 min) — 20 °C/min — 250 °C (0 min) |
| Analysis Duration | < 12 minutes |
It reduces the length of the analysis by up to five times when compared to traditional approaches.
The part number is CP8138.