Agilent 500 Ion Trap LC/MS SelecTemp Technical Overview

SelecTemp is a temperature-programmable atmospheric pressure ionization (API) drying gas control and is a unique feature of the Agilent 500 Ion Trap LC/MS. Positive and negative temperature programming ensures the optimum drying gas temperature for all mobile phase compositions in gradient separations resulting in greater sensitivity and productivity.


Agilent 500 Ion Trap LC/MS SelecTemp Technical Overview - cover page
Brand
Agilent
Document type
Product Leaflet
Language
English
Pages
4
File format
PDF
File size
384 KB
Published
05 July, 2012
Updated
29 September, 2023
MD5 checksum
7093C84DCBECAC190B2E03D7D8B7F144

About this manual

This document provides a technical overview of the SelecTemp feature available on the Agilent 500 Ion Trap LC/MS. SelecTemp is a temperature-programmable atmospheric pressure ionization (API) dry-gas control system designed to optimize drying gas temperature for all mobile phase compositions during gradient separations.

The feature allows users to specify starting and ending temperatures with hold times, while the rate is calculated based on the full run time. Individual segments can be adjusted to lower or higher values as needed. This capability ensures optimum desolvation of droplets, reducing interface contamination and improving sensitivity for thermally labile compounds.

What's inside

  • Introduction
  • Experimental Conditions
  • Temperature SelectTemp Control
  • Benefits

Frequently asked questions

What is SelecTemp?

SelecTemp is a temperature-programmable atmospheric pressure ionization dry gas control feature of the Agilent 500 Ion Trap LC/MS.

How does SelecTemp improve sensitivity for thermally labile compounds?

It provides a factor of three improvement in signal-to-noise by lowering the drying gas temperature from 330 °C to 300 °C during the run.

What are the benefits of using SelecTemp?

Benefits include increased sensitivity and selectivity, reduced interface contamination, improved throughput, simplified setup, and automatically recorded parameters for GLP purposes.

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