DuraGuard Columns: GC Columns with Built-In Protection
This document introduces Agilent DuraGuard columns, which feature built-in deactivated fused silica tubing to act as guard columns, retention gaps, or MSD transfer lines. These columns eliminate the need for unions, thereby preventing leaks, dead volume, and activity problems that can degrade peak shape and contaminate detectors. The text explains the benefits of this design for analyzing samples with low levels of chemically active compounds or nonvolatile residues.
| Guard column length | 5-10 meters |
|---|---|
| Retention gap length | 3-5 meters |
| Column type | Deactivated fused silica tubing |
| Part number example | 122-5532G |
They minimize front-end contamination, increase column lifetime, aid in focusing samples for excellent peak shape, and minimize MSD source contamination without leaks or added activity.
They are made with a single, continuous piece of fused silica tubing, which eliminates the need for unions that are prone to leaking.
Periodic cutting or trimming is usually required upon a build-up of nonvolatile residues, indicated by the onset of peak shape problems.