Agilent LC/TOF-MS Application Note: Identification of Unknown Reaction By-Products in Epoxyphenolic-Based Food Can Coati

This article illustrates how time-of-flight mass spectrometry can be used in the safety evaluation of new and existing can coatings used in the food industry. The accurate mass provides information for the parent compound and fragment ions greatly increase the confidence in the identification process.


Agilent LC/TOF-MS Application Note: Identification of Unknown Reaction By-Products in Epoxyphenolic-Based Food Can Coati - cover page
Brand
Agilent
Document type
Application Note
Language
English
Pages
6
File format
PDF
File size
211 KB
Published
12 June, 2012
Updated
29 September, 2023
MD5 checksum
66B3E404E7379255D263ECE8CC23D1C2

About this manual

The document describes a method for evaluating the safety of new and existing can coatings used in the food industry. It focuses on identifying potential migrants from epoxyphenolic lacquers into foodstuffs, specifically those derived from bisphenol A diglycidyl ether (BADGE). The study utilizes liquid chromatography coupled with time-of-flight mass spectrometry (LC/TOF-MS) to analyze solvent extracts of coated metal panels.

What's inside

  • Application
  • Introduction
  • Experimental
  • Sample Extraction
  • LC Conditions
  • MS Conditions
  • Results and Discussion
  • Conclusions

Frequently asked questions

What is the purpose of this application note?

This document illustrates how time-of-flight mass spectrometry can be used in the safety evaluation of new and existing can coatings used in the food industry.

What is the flow rate for the LC conditions?

The flow rate for the liquid chromatography conditions is 0.2 mL/min.

At what temperature was the gas set during MS analysis?

The gas temperature used in the mass spectrometry conditions was 300 °C.

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