This Application Note demonstrates the excellent linearity performance of the Agilent 1120 Compact LC autosampler. The system can be used to perform linearity calibration for samples ranging from 1 to 100 µL. The results show that the Agilent 1120 Compact LC autosampler has a linearity coefficient of R2 > 0.9999.
The document evaluates the autosampler precision and linearity of the Agilent 1120 Compact LC system. It details a study where Tramadol was injected at varying volumes ranging from 1 µL to 100 µL to test performance across a wide analytical range.
Results indicate excellent retention time precision with an RSD < 0.07% and peak area precision with an RSD < 0.5%. The injector linearity showed a coefficient of correlation (R²) greater than 0.9999, confirming the system's suitability for pharmaceutical QA/QC.
The study covers a wide range from 1 µL to 100 µL injected.
The solution concentration used was 100 ng/µL.
The observed linearity correlation (R²) is greater than 0.9999.