This application note describes a fast and sensitive method for the determination of bisphenol-A in epoxy resins using GPC with an evaporative light scattering detector (ELSD). The method uses a narrow bore column and high flow rate for rapid separation, and Agilent ELSD provides excellent sensitivity and signal-to-noise ratio.
Bisphenol-A is an intermediate material in the production of epoxy resins. This document outlines a fast Gel Permeation Chromatography (GPC) method designed to monitor residual levels of bisphenol-A using a narrow bore column at high eluent flow rates.
The analysis utilizes Evaporative Light Scattering Detection (ELSD) with an Agilent ELSD detector, chosen for its improved signal-to-noise ratio and independence from dn/dc effects. The recommended system configuration includes the PLgel 5 um MiniMIX-D column.
It describes a fast GPC method for monitoring residual levels of bisphenol-A.
The nebulizer temperature is set to 50 °C and the evaporator temperature is 70 °C.
The recommended flow rate is 1.0 mL/min.