This application note describes a method for the analysis of dialkyl phthalates using an Agilent PLgel 5 µm 50Å column using gel permeation chromatography.
Phthalates are widely used as softeners for polyvinylchlorides but face increasing scrutiny due to health concerns. This document outlines a straightforward method for their analysis using gel permeation chromatography (GPC) with an Agilent PLgel column.
The procedure utilizes a single high-performance, low pore size Agilent PLgel 5 µm column (300 x 7.6 mm). Analysis is performed at a flow rate of 1.0 mL/min with a Refractive Index (RI) detector to achieve rapid separation and good resolution for small-molecule dialkyl phthalates.
The recommended flow rate is 1.0 mL/min.
The RI (refractive index) detector is specified for use.