Industrial

This document introduces the method for determining As in samples containing high concentration of chloride using Agilent 4500 ICP-MS.

This document describes two methods for analyzing glyphosate, one is pre-column derivatization and the other is post-column oxidation.

Agilent 3000 Micro GC configured with two performance-enhanced modules provides a fast and accurate solution for landfill gas component analysis. The individual components are baseline separated in less than 30 seconds by a two-channel configured Micro GC. With this solution, landfill gas can be monitored and controlled easily.

This application note describes a fast HPLC method for the analysis of DNPH derivatized carbonyls found in air samples. The method employs a 1.8-μm StableBond C18 column and a UV detector, and can separate and identify a standard of the major 13 DNPH derivatized carbonyls. An air sample is analyzed in under 10 minutes and found to contain several carbonyls.

This document describes the analysis of 19 pharmaceuticals in positive ion mode and 11 pharmaceuticals in negative ion mode using solid phase extraction (SPE) and liquid chromatography/tandem mass spectrometry (LC/MS/MS). The analysis was performed at low picogram level on column without any derivatization. Good linearity was observed for analytes from 1 pg to 1 ng on column. Repeatability from six injections of analytes at 5 pg on column showed RSDs below 15%, for all target compounds except for fluoxetine at 23%.

Peptide Mapping of a Monoclonal Antibody using a Microfluidic-based HPLC-Chip coupled to an Agilent Accurate-Mass Q-TOF LC/MS

This note describes the Pressure Controlled Tee (PCT) configuration for rapid and universal GC/MS backflushing applied to selected reaction monitoring experiments on the Agilent 7890 GC used with the Agilent 7000 Series Triple Quadrupole Mass Spectrometer. This means that rapid backflushing and quick column and inlet maintenance without venting the MS system can be incorporated without a loss in detection limits using a simple PCT configuration.

The OPA2107 is a dual operational amplifier with features including very low noise, low offset voltage and drift, low input bias current, fast settling time, etc. It is suitable for precision and low-noise analog circuitry and can be used to upgrade designs currently using BIFET amplifiers.

This datasheet provides the characteristics and specifications of the OPA21 op-amp.

This article introduces a fast GC-FID method for the analysis of mineral oil in environmental samples using a low thermal mass system. The fast oven temperature programming achieved by the low thermal mass system dramatically reduced the analysis cycle time and increased the sensitivity. The regulated method requirements are met for the environmental analysis of the C10-C40 hydrocarbon fraction in soil and water extracts using splitless injection with an analysis time less than three minutes. Cool-down time is less than two minutes, resulting in an injection-injection cycle time of five minutes. Method performance criteria, including repeatability, linearity and solute discrimination, are presented.

A profile-directed biomarker discovery approach involving initial differential expression analysis followed by targeted identification of differentially expressed proteins was used in this study. Using Agilent platforms such as a Multiple Affinity Removal (MARS) column, a 1200 Series HPLC-Chip/MS and a 6520 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) LC/MS, excellent reproducibility in retention time and intensity measurement, and outstanding accuracy in mass measurement and sensitivity over a wide dynamic range were achieved. Differential analyses using MassHunter Mass Profiler and MassHunter Mass Profiler Professional (MPP) software enabled the comparison between spiked and non-spiked plasma samples. Subsequent targeted MS/MS analysis on a Q-TOF LC/MS followed by a database search using Spectrum Mill helped identify the spiked protein.

This Application Note demonstrates the use of rapid resolution liquid chromatography in conjunction with tandem mass spectrometry to study the plasma stability of phar- maceutical compounds belonging to four different drug classes. The Agilent 1200 Series Rapid Resolution LC system (RRLC) provided fast separation of compounds and internal standard in all samples. The Agilent MassHunter Optimizer software identi- fied compound-specific MS parameters such as the most abundant product ions, opti- mal fragmentor voltages and collision energies. Taken together, robust methods for a larger set of compounds could be developed within a short period of time.

This document introduces the advantages of Agilent 7700x ICP-MS technology in drinking water analysis. This technology uses the 3rd generation Octopole Reaction System (ORS3) technology to effectively remove polyatomic interferences. He mode is simple and easy to use, and the 7700x ICP-MS can remove all polyatomic interferences in a single set of conditions without requiring any prior knowledge about the sample, and without the need for complex mathematical corrections. This makes setup easier, detection limits are lower, analysis is faster, and interference removal is improved, especially for the difficult plasma-based interferences affecting iron and selenium. Currently, Se detection limits of less than 20ppt are routinely achievable in He mode.

This application note describes a method for the analysis of impurities in fine chemical octyl-dimethyl-4-aminobenzoate using the Agilent 1290 Infinity LC and ZORBAX RRHT and RRHD 1.8 µm columns

The document describes the features and characteristics of OPA177 precision bipolar operational amplifier produced by Burr-Brown Corporation. This product has low offset voltage, low drift, high open-loop gain, and low quiescent current, making it suitable for precision instrumentation, data acquisition, test equipment, bridge amplifier, and thermocouple amplifier applications.