Agilent manuals, page 15
Agilent Pharmaceutical residual solvents using static headspace GC-FID/MS analysis General-purpose method of Manual
This application note describes a universal method for the analysis of residual solvents in pharmaceuticals using static headspace GC-FID/MS. The method is capable of analyzing more than 50 solvents in a single run. The method has been optimized for the three classes of residual solvents defined by the ICH, allowing for the qualitative and quantitative analysis of all three classes at appropriate concentrations.
Agilent Pairoraiza GC/MS analysis Its application Capillary Flow Technology in 1 Manual
Applying Agilent's unique technology, the Agilent Dual Shot EGA GC/MS system can change the inlet line and maintain the injection port without MS vacuuming, so as to realize high-efficiency, accurate and automatic analysis.
Agilent Pairoraiza GC/MS analysis Its application Capillary Flow Technology in 2 Manual
Agilent 1120 Compact LC Manual
This document describes a method for USP purity analysis of pravastatin sodium using Agilent 1120 Compact LC. The system suitability parameters of the method (including resolution, recovery and repeatability) meet USP requirements. The detector of Agilent 1120 Compact LC has a linear response to related compound A, with a detection limit of 0.09 µg/mL.
Agilent 1200 Manual(2)
This document introduces the Agilent 1200 Series LC Method Development Solution and Agilent Easy Access Software, which can be used to check reaction processes, find the best chromatography column and check impurities. The system supports up to 8 different columns. The superuser can define analysis methods for each installed column, including the appropriate balancing method. The superuser can also define projects for different user groups and individual users. Permission levels and priorities can be set for users and groups. For example, the highest priority can be given to reaction monitoring samples, so that these samples can be analyzed immediately. After the analysis is complete, the system can send the results to the relevant users by email.
Agilent 6460 Manual
This study uses Agilent 6460 high performance liquid chromatography coupled to mass spectrometry (LC-MS/MS) to perform high-sensitivity analysis of clenbuterol in pork. The results show that under the optimal detection conditions, the average recovery rate of clenbuterol at the addition level of 0.1 ng/g is 98.2%, the relative standard deviation is 3.5%, and the limit of quantification is 0.02 ng/g. This method has good sensitivity and accuracy and is suitable for the detection of clenbuterol in pork.
Agilent 1200 Manual(1)
This application note describes the methods for conventional HPLC analysis and Rapid Resolution LC (RRLC) analysis of Radix Bupleuri, a traditional Chinese medicine. The comparison of the fingerprint chromatograms of multiple Radix Bupleuri samples showed that different herbal medicines from different sources have different peak profiles. The method for Agilent 1200 Series evaporative light scattering detector (ELSD) was optimized to obtain maximum response. A quantitative method was developed to measure six glycosides in the herbal medicine and its preparations.
Agilent 1200 Manual
This document describes the application of Agilent 1200 series Evaporative Light Scattering Detector (ELSD) for the analysis of herbal preparations (Chinese herbal raw materials). HPLC separation methods were optimized for five herbal medicines and their formulations, and sample pre-treatment methods were also explained.
Agilent Reduction of solvent consumption by the size of the column Manual
This document describes a method to reduce solvent consumption by decreasing the inner diameter (ID), length, and particle size of LC columns, resulting in a maximum reduction of 86% in solvent consumption and a maximum reduction of 67% in analysis time. The experiment used ZORBAX Eclipse Plus C18 columns for isocratic separation of a diet carbonated beverage and gradient analysis of a hickory smoked seasoning. By replacing the column with reduced ID, length, and particle size, it is demonstrated that solvent consumption can be reduced and analysis time can be shortened.
Agilent ZORBAX Eclipse Plus C18 Manual
This document describes the improvement of simvastatin analysis performance using Agilent ZORBAX Eclipse Plus C18 columns with different particle sizes. By making simple adjustments, the USP method can be adapted to Rapid Resolution Eclipse Plus C18 3.5µm columns or Rapid Resolution HT Eclipse Plus C18 1.8µm columns, resulting in shorter analysis time and significant solvent savings.
Agilent Improvement of cycle time robustness of the GC / MS method with back flash Capillary Flow Technology Manual
Agilent 7000A Manual
This document introduces a method for the quantification of nitro polycyclic aromatic hydrocarbons in atmospheric particulate matter using an Agilent 7000A triple quadrupole gas chromatography mass spectrometer.
Agilent 6410A Manual
This document describes the method of analyzing pharmaceuticals in water samples using the Agilent G6410A triple quadrupole mass spectrometer (QQQ) with HPLC/MS/MS. The method was developed following the guidelines of EPA method 1694. Four different chromatographic gradients and LC conditions were used to accommodate the polarity and systematics of various pharmaceuticals. Additionally, analysis using positive and negative ion electrospray was performed for quantification and qualification of each compound.
Agilent high-speed Separating high-throughput (RRHT) And column ChromSword Software makeuse And Agilent 1200SL Of artemisinin by the system analysis Manual
This document describes a simple isocratic method for analyzing artemisinin using the Agilent 1200SL system with high-speed separation high-throughput (RRHT) columns and ChromSword software. The method development was automated using the ChromSword software, which helped in selecting the optimal column. By utilizing a fully automated unmanned method development program, the analysis time was significantly reduced.
Agilent GC/MS And system Agilent Fiehn GC/MS Metabolomics RTL Metabolite identification in plasma by library Manual