This document introduces a fast method for acquiring 2D and 3D data called Automatic Spectral Compression (ASCOM). ASCOM can use standard data processing methods to achieve very rapid acquisition of 2D and 3D data without losing information. This can improve 2D data by 2-5 times and 3D data by 4-25 times. This capability is standard in BioPack for experiments run on an Agilent NMR system.
This document provides a technical overview of Automatic Spectral Compression (ASCOM), a feature standard in Agilent BioPack for NMR systems. ASCOM allows for the rapid acquisition of 2-D and 3-D data without loss of information by automating the process of spectral folding. This capability is particularly useful for reducing the long acquisition times often required for multi-dimensional NMR experiments on large molecules.
It permits very rapid acquisition of 2-D and 3-D data without loss of information using standard data processing.
Improvements of a factor of 2-5 are feasible for 2-D data.
Improvements of a factor of 4-25 are feasible for 3-D data sets.