Agilent Triple Quadrupole LC/MS Systems Triggered MRM Technical Overview

Triggered MRM is an analytical method available for all Agilent Triple Quadrupole LC/MS systems, which can perform simultaneous quantification and confirmation


Agilent Triple Quadrupole LC/MS Systems Triggered MRM Technical Overview - cover page
Brand
Agilent
Document type
Product Leaflet
Language
English
Pages
4
File format
PDF
File size
112 KB
Published
05 July, 2012
Updated
30 September, 2023
MD5 checksum
1F7682631182DBC5D6F7C7F5CD8DC06B

About this manual

Triggered MRM (tMRM) is an analytical method available for all Agilent Triple Quadrupole LC/MS systems. It combines Multiple Reaction Monitoring (MRM) with the generation of a product ion spectrum to enable library identification and confirmation within a single run, thereby decreasing analysis time and increasing throughput.

What's inside

  • Technical Overview
  • How tMRM Acquisition Works
  • tMRM Library Searching
  • Avoiding False Positives
  • Rapid Quantitative Analysis
  • Conclusions

Frequently asked questions

How long does it take to acquire all MRM transitions for a target analyte?

Acquiring all 10 MRM transitions takes less than 50 ms.

How many data points are acquired across each peak compared to a typical product ion scan?

More data points are acquired because the tMRM cycle is faster, whereas a typical scan takes about 200 ms.

What is the maximum number of MRM transitions defined for each target analyte?

Up to 10 MRM transitions (primary and secondary) are defined for each target analyte.

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