This document is a technical overview of Agilent GC Q-TOF mass spectrometer.
This document provides a technical overview of the Agilent LC/MSD TOF, an orthogonal acceleration time-of-flight (oa-TOF) mass spectrometer designed for the analysis of small and large molecules. It details the instrument's operation using atmospheric pressure ionization sources and describes the ion path through the vacuum system, including octopole ion guides and ion mirrors.
The text explains the fundamental physics of time-of-flight analysis, presenting equations that relate flight time to mass-to-charge ratio. It also covers the instrument's calibration process, which involves determining coefficients through non-linear regression and applying second-pass corrections to achieve high mass accuracy.
It is used for the analysis of both small and large molecules.
The flight tube is about one meter in length.
The amplifier is operated at 5 MHz.