This technical note describes the new features of the Agilent 1100 Series LC/MSD Trap software Version 4.2, including the Dissect function, the MASCAT program, and the automatic gain calibration function.
The document details new features in Agilent LC/MSD Trap software Version 4.2. Key additions include the optional Dissect function, which automates the identification of minor sample components like drug metabolites in complex chromatograms using fuzzy logic and statistical analysis. The software also includes automatic gain calibration to ensure consistent results across different days and instruments.
The Dissect algorithm automates the location of minor sample components, such as drug metabolites, in complex MS datasets by generating extracted ion chromatograms and using fuzzy logic to group peaks.
MASCAT concatenates multiple Mascot generic format (*.mgf) files, allowing for a consolidated database search of spectra from multiple two-dimensional LC/MS/MS analyses.