This paper describes the use of gas chromatography coupled with triple quadrupole mass spectrometry (GC/MS/MS) to screen pesticides in Traditional Chinese Medicine (TCM) at levels as low as 1 ppb. The Triple Quadrupole mass spec- trometer, when used in Multiple Reaction Monitoring (MRM) mode, can dramatical- ly remove matrix interferences and significantly increase the effective signal-to- noise ratio (S/N).
The document details a methodology for screening pesticide residues in Traditional Chinese Medicine (TCM) at ultra-low concentrations using gas chromatography coupled with triple quadrupole mass spectrometry. The primary focus is on the use of Multiple Reaction Monitoring (MRM) mode to achieve high sensitivity and reduce matrix interference.
| Detection Limit | 1 ppb |
|---|---|
| MRM Capability | 500 MRM/sec |
| Dwell Time | 5 ms |
The Agilent 7000A GC/MS/MS is used to screen pesticides in Traditional Chinese Medicine.
Multiple Reaction Monitoring (MRM) mode is used to reduce matrix interference.