This paper introduces a new method for environmental semivolatiles detection using a triple-axis detector (TAD) to achieve femtogram GC/MSD detection limits with improved sensitivity. The method uses liquid-solid extraction (LSE) with C18 disks or columns for sample extraction, 1 µL hot split-less injection for sample injection, and MS operating in full-scan mode. This method significantly improves the sensitivity to the femtogram level when measuring acids, bases, neutrals, and pesticides in drinking water and source water.
The document addresses the challenges of analyzing semivolatiles at very low levels, such as those found in drinking water. It outlines a specific method requiring high sensitivity to detect acids, bases, neutrals, and pesticides concurrently.
To achieve these detection limits, the recommended setup utilizes an Agilent 7890A or 6890N Gas Chromatograph equipped with an EPC PTV inlet in cold splitless mode. The system is coupled with an Agilent 5975C Mass Selective Detector (MSD) featuring a Triple-Axis Detector (TAD) operating in Selected Ion Monitoring (SIM) mode with Trace Ion Detection enabled.
A 2-uL injection was used for all data presented.