This document describes a method for studying fifteen of the most common and important organophosphorus pesticides (OPs) using the Agilent 6820 gas chromatograph (GC) equipped with the new nitrogen-phosphorus detector (NPD). The 6820 GC-NPD demonstrated good linearity for concentrations of pesticides range from 1 to 500 ng/mL (R2 >0.999) for most compounds. All OPs produced high signal-to-noise ratios for splitless injections at 10 ng/mL (ppb) concentrations with the NPD detector. Instrumental limits of detection for most OPs studied were at low or sub-ppb concentrations. This suggests the 6820 GC with an NPD is well suited for OP pesticide residue determinations in foods, water, or other samples.
The document describes the use of the Agilent 6820 gas chromatograph equipped with a new nitrogen-phosphorus detector (NPD) for studying fifteen common organophosphorus pesticides. The study demonstrates that the system provides good linearity and high signal-to-noise ratios, making it well-suited for determining pesticide residues in foods and water.
| Inlet temperature | 250°C |
|---|---|
| Injection mode | Splitless |
| Carrier gas | He, head pressure: 12 psi |
| Detector temperature | 326 °C |
| Linearity range | 1 to 500 ng/mL |
The system demonstrated good linearity for concentrations ranging from 1 to 500 ng/mL.
It is best to use acetone or hexane, as solvents like methylene chloride can damage the detector.
Cerity Networked Data System (NDS) for Chemical QA/QC software was used.