This application note details an application kit for the screening of 25 compounds considered in forensic and toxicology analyses using an Agilent 1200 Series LC system with an Agilent 6410 Triple Quadrupole LC/MS.
The document describes an analytical method developed by Agilent Technologies to screen for 25 compounds considered in forensic and toxicology analyses. The method utilizes an Agilent 1200 Series LC system coupled with an Agilent 6410 Triple Quadrupole LC/MS.
The study demonstrates the use of Agilent Poroshell 120 EC-C18 and SB-C18 superficially porous columns to analyze a 25-component Toxicology Test Mixture. The method is optimized for faster flow rates to reduce analysis time while maintaining resolution, and it includes a demonstration of analyzing illicit drug residues extracted from US currency.
The $1 bill sample was extracted in 7 mL of methanol and ultrasonicated for 30 minutes.