Industrial

TMS320C5x and TMS320LC5x are digital signal processors with a powerful 16-bit TMS320C5x CPU. They have a single-cycle instruction execution time of 20, 25, 35, and 50 ns for 5V operation, and 25, 40, and 50 ns for 3V operation. They also feature single-cycle 16x16-bit multiply/add, a maximum addressable external memory space of 224Kx16-bit, on-chip program ROM with sizes ranging from 2K to 32Kx16-bit, on-chip program/data RAM (SARAM) with sizes ranging from 1K to 9Kx16-bit, on-chip dual-access program/data RAM (DARAM) with a size of 1K, full-duplex synchronous serial port for coder/decoder interface, time-division-multiplexed (TDM) serial port, hardware or software wait-state generation capability, on-chip timer for control operations, repeat instructions for efficient use of program space, buffered serial port, host port interface, multiple phase-locked loop (PLL) clocking options (x1, x2, x3, x4, x5, x9 depending on the device), block moves for data/program management, on-chip scan-based emulation logic, boundary scan, and five packaging options. It also has low power dissipation and power-down modes, consuming 47 mA (2.35 mA/MIP) at 5V and 40 MHz.

This study demonstrates the use of Agilent’s new MS/MS spectral metabolomics library to elucidate the identification of several amino acids that are important in malaria metabolism.

This document describes how a pharmaceutical company maximizes efficiency in early drug discovery by using Agilent Analytical Studio Reviewer (ASR) for high-throughput LC/MS analyses to determine the correct compounds. The company is one of the largest pharmaceutical companies in Japan, with a focus on developing drugs in the therapeutic categories of urology, immunology and infectious diseases, oncology, neuroscience, diabetes mellitus complications, and metabolic diseases.

This application note describes an improved microextraction method for sample preparation that can be used to analyze a variety of therapeutic categories of pharmaceuticals on an Agilent Poroshell 120 column. The method is simple, fast, economical, and effective for therapeutic drug monitoring and forensic chemistry.

This document describes the method of fast refinery gas analysis using the Agilent 490 Micro GC QUAD. The authors demonstrate the analysis results obtained in about two minutes through experimental results. The document also introduces the features of the equipment and the materials used.

This application note presents a method developed using the Agilent 1290 Infinity LC Method Development System and the Agilent Method Scouting Wizard software for the analysis of 20 amines derived from banned azo dyes. Different columns, mobile phases, and temperatures were screened in an automated manner. Initial screening analyses were performed using LC-MS, while method optimization was done with diode-array detection. The performance of the final method was evaluated.

This document describes the analysis of azo dyes using the Agilent 1290 Infinity LC System and the 60 mm Max-Light high sensitivity flow cell. The performance of the high sensitivity method is investigated by comparing the results with those obtained using a standard flow cell.

This application note describes a method for the rapid separation of recombinant human erythropoietin using the Agilent ZORBAX 300SB-C18 1.8 µm Rapid Resolution High Definition (RRHD) column. This method has increased sensitivity, reduced separation time and improved run-to-run reproducibility, which is in great demand by biotechnology and pharmaceutical companies. The C18 StableBond coating technology provides increased sensitivity, exceptional pH, and thermal stability. The use of a 1.8-µm column designed for UHPLC systems significantly reduces analysis time, critical for increasing the efficiency of QC for protein primary structure analysis. The data presented here focus on the fast separation of various recombinant human erythropoietin isoforms. Like many other biomolecules, recombinant EPO protein exhibits heterogeneity due to modifications that occur during manufacturing. Methods are optimized for flow rates, gradient and reproducibility under acidic conditions that contain trifluoroacetic acid.

Scalability of Agilent Columns Across HPLC and UHPLC Instruments

This Application Note describes purification of poly- and monoclonal antibodies from different media backgrounds constructed to mimic those encountered during antibody screening, production, and scale-up in commercial settings.

This article describes a method for quantifying antioxidants (vitamin C) and preservatives (citric acid, benzoic acid) in orange juice. The method can be effectively applied by food manufacturers for quality control of food additives.

This application note demonstrates the analysis of acetone, methanol, and ethanol in air using the Agilent 490 Micro GC equipped with a CP-Wax 52 CB column channel. The Agilent 490 Micro GC offers ease-of-use and fast analysis, providing results in less than 30 seconds. It can be optionally equipped with a portable field case for measurements in locations without carrier gas or power.

This paper introduces the influence of silica particle size and pore size on insulin separation. The results show that a larger pore size and a smaller particle size lead to better separation of insulin. Agilent Poroshell 120 column with pore size (120Å) and superficially porous particle size (2.7µm) is the best choice for insulin analysis.