Agilent Manuals

This document describes a method for the identification and quantification of pesticides and herbicides in water using liquid chromatography (LC) and diode array detector (DAD). The method was developed not only for the separation and detection of 17 common herbicides but also 19 additional herbicides and pesticides of possible interest. The methodology consists of: • Sample preparation by Solid Phase Extraction using Empore Disk technology • Separation by HPLC • Peak identification by Spectral Library Search using a Diode Array Detector

This document describes a method for sample cleanup of tobramycin in serum using pre-SPE derivatization with orthophthalaldehyde (OPA) to enhance selectivity. The method improves the cleanup of tobramycin from a biological matrix by pre-SPE derivatization with OPA and enhances detection sensitivity through fluorescence detection of the derivative formed.

This application note provides a method for enhancing the detection sensitivity of tobramycin using pre-column derivatization with orthophthalaldehyde (OPA). The method can be used to analyze poorly detectable polar compounds, such as tobramycin.

This application note describes the analysis of 45 neutral, basic, and acidic veterinary drugs in different meat matrices down to the MRLs (0.01 ppm) of the Japanese Positive List.

This application note describes how to remove salts from samples using StratoSpheres™ PL-MIXED MP cartridges to protect HPLC columns.

This application note describes the LC-MS/MS method for determining malachite green (MG) and crystal violet (CV) using Pursuit™ XRs.

This application note describes a rapid and robust method for profiling carbohydrates in fruit juices using HPLC with ELSD.

This application note describes a method for the high-sensitivity analysis of betaine in Chinese lycium using high-performance liquid chromatography (HPLC) with an electrochemical detection (ELSD). This method has high sensitivity and is suitable for the determination of betaine in plasma and other biological samples.

This article describes the effective analysis of low chromophore polymer additives using HPLC with ELSD. ELSD is a detection technique that is suitable for compounds with weak or no UV chromophores. The article mentions that Varian's evaporative light scattering detector is highly sensitive to a wide range of compounds and is ideal for this application. Analysis of polymer additives has been limited by the suitability of the detection method, as many additives lack a UV chromophore and are not suitable for refractive index detection. Therefore, there is a need for accurate, reliable, and robust analytical methods. The article also discusses the importance of polymer additives in polymers and their impact on polymer characteristics.

This document describes a method for the rapid identification of illegal dyes in paprika oil using HPLC with ELSD technology. Sudan dyes I-IV, which are categorized as class 3 carcinogens by the International Agency for Research on Cancer, are not approved for use in food products. The document also discusses the characteristics of Sudan dyes and regulatory requirements.

This application note describes a method for detecting combinatorial libraries using high performance liquid chromatography (HPLC) and low temperature ELSD. The method can detect low molecular weight degradation products in DMSO without interference from DMSO. This method is also discussed for its use in highlighting unstable compounds in the early stages of drug discovery.

This application note describes the analysis of complex triglycerides in borage oil using LC-ELSD.

This document describes the use of slip agents to control the coefficient of friction of packaging materials, in order to increase production efficiency and improve packaging line operations. It introduces common slip agents and their physical properties.

This application note describes a high resolution method for analyzing triglycerides in vegetable oils. The method uses the Varian evaporative light scattering detector, which has good selectivity and sensitivity for compounds such as triglycerides that lack UV chromophores.

Application Note SI-01229 introduces the benefits of using a low-temperature ELSD for the analysis of herbicides by HPLC.