Agilent 6400 Series Triple Quad LC/MS Concepts Guide
This guide explains how the Agilent 6400 Series Triple Quadrupole LC/MS system works, including its hardware and software components. It covers configurations like ESI, APCI, and APPI ion sources, and how to use the Agilent MassHunter Workstation Software for data acquisition. The guide also details sensitivity improvements through technologies like iFunnel and Jet Stream, and how to set up and optimize instrument parameters for various applications such as food safety, environmental studies, and bioanalysis.
The guide includes sections on inner workings of triple quadrupole MS versus single quadrupole MS, sensitivity enhancements, and software tuning and acquisition methods. It is designed to help users understand and operate the system effectively, with real-time monitoring and data analysis capabilities.
The system can be used to quantitate trace organic compounds in complex matrices for food safety studies, environmental studies, drug discovery, toxicology, forensics, and bioanalysis.
The Agilent 6460 and 6490 Triple Quadrupole LC/MS systems are the only models in the series that can use the Agilent Jet Stream Technology.
Supported ion sources for normal flow LC/MS include ESI, APCI, APPI, and MMI.