Advantages of Orthogonal Nebulizer Orientation in Electrospray for Quadrupole and Ion Trap Mass Spectrometers Technical

This document introduces the Gain Normalization function implemented in the ChemStation G1701EA (E.02.xx) software. It includes new Gain selection items and expanded Gain Normalization to chemical ionization modes. The advantages of Gain Normalization are described, and how to specify Gain settings in methods are introduced.

Brand: Agilent
Document type: Other
Language: English
Pages: 7
File format: PDF
File size: 105 KB
Published: 05 July, 2012
Updated: 30 September, 2023
MD5 checksum: 1DA7E630630434796567E4F51EE7ABDF
PDF: Advantages of Orthogonal Nebulizer Orientation in Electrospray for Quadrupole and Ion Trap Mass Spectrometers Technical PDF

About this manual

This document is a technical note titled "Advantages of Orthogonal Nebulizer Orientation in Electrospray for Quadrupole and Ion Trap Mass Spectrometers" authored by Dr. Robert D. Voyksner of LCMS Limited. It was published by Agilent Technologies in March 2001.

What's inside

Introduction
Experimental Setup
Ruggedness Study Results
Ion Trap Analysis Comparison
Precision and Sensitivity Data

Frequently asked questions

How does orthogonal nebulization affect the contamination of the sampling orifice and ion optics?

Off-axis (orthogonal) nebulization reduces the contamination of the sampling orifice and ion optics compared to conventional on-axis nebulization.

What is the average standard deviation for the analysis of 800 hydrolysis samples over 15 days?

The average standard deviation was found to be only 2.6%.

What is the measured peak area variance for off-axis nebulization over 60 plasma extracts?

The off-axis results show less than 10% variance in measured peak area over the 60 samples.

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