Introduces the performance improvements of the Agilent 1200 Series LC, including detection limits, analysis speed and solvent consumption, and provides experimental equipment configuration.
This document is a technical note describing how to improve the chromatographic power of the Agilent 1200 Series Liquid Chromatography (LC) system. It focuses on upgrading the Variable Wavelength Detector (VWD) to the SL Plus model and utilizing ZORBAX RRHT columns with sub-2-micron particles.
The run time is shortened from 15 minutes to 3 minutes, representing a fivefold increase in analysis speed.
Solvent consumption can be cut by 50 percent.
The signal-to-noise ratio increases by a factor of three.