Agilent SampliQ OPT uses Optimized Polymer Technology (OPT), a novel polyamide chemistry (patent pending). The result is a resin that exhibits retention for both polar and nonpolar compounds based on the balanced hydrophilic and hydrophobic properties of the polymer.
Agilent introduces the SampliQ OPT solid-phase extraction (SPE) cartridges, which utilize a novel polyamide chemistry known as Optimized Polymer Technology (OPT). This technology provides a balanced hydrophilic/lipophilic character, allowing for the retention of both polar and nonpolar compounds, including basic, neutral, and acidic substances. The document highlights that these cartridges are robust, stable in pH ranges from 0 to 14, and capable of withstanding drying between conditioning and equilibration steps without affecting reproducibility.
| pH Stability Range | 0 to 14 |
|---|---|
| Cartridge Volume (Part 5982-3013) | 1 mL |
| Cartridge Volume (Part 5982-3036) | 3 mL |
| Cartridge Volume (Part 5982-3067) | 6 mL |
| Recommended Flow Rate | 1 mL/min |
Yes, the cartridges are robust and can run dry between the methanol conditioning and water equilibration steps without affecting reproducibility.
The flow through the cartridge should be no faster than 1 mL/minute for the loading step.
Compounds that are both hydrophilic (low log P) and strongly basic (pKa > 10) or strongly acidic (pKa < 3) will not be effectively retained.