The Varian 400-DS Dissolution Apparatus sets the performance standard for drug-release testing of medical devices. It is the first dissolution apparatus built specifically for small-volume dissolution testing of combination drug products that meets all compendial requirements for USP Apparatus VII. The 400-DS provides compliance with 21 CFR Part 11 guidelines and brings an unprecedented level of convenience, throughput and efficiency to your quality control and R&D operations.
The Varian 400-DS Dissolution Apparatus sets the performance standard for drug-release testing of medical devices. It is specifically built for small-volume dissolution testing of combination drug products and meets all requirements for USP Apparatus VII.
The apparatus features an integrated autosampler to save laboratory bench space. Key specifications include a sample reciprocation tolerance of 20.0 mm, a dip rate range of 5-35 DPM with 0.59% accuracy, and temperature control ranging from ambient +5 up to 50 °C.
| Sample reciprocation tolerance | 20.0 mm (+ 1.0mm) |
|---|---|
| Dip rate range | 5-35 DPM |
| Temperature control range | ambient +5 up to 50 °C |
| Media volume (5 mL cell) | 3-5 mL |
| Test duration | 1 hour to 28 days |
| Input voltage | 115/230 V AC; 50/60 Hz |
| Dimensions | 21 in. (w) x 23 in. (h) x 23.5 in. (d) |
It sets the performance standard for drug-release testing of medical devices, specifically for small-volume dissolution testing.
Yes, it is the first dissolution apparatus built specifically to meet all requirements for USP Apparatus VII.
The apparatus supports 3-5 mL for a 5 mL cell or 8-12 mL for a 10 mL cell.