Agilent ZORBAX Rapid Resolution High Definition SB-C18 Threaded Column handbook(1)

Agilent ZORBAX Rapid Resolution High Definition (RRHD) SB-C18 column is a high-performance particulate C18 packing for high-speed and high resolution reversed-phase HPLC and UHPLC. This column is particularly well-suited for use with aggressive mobile phases (for example, pH < 2, high ionic strength, ion-pair additives, etc.) since the steric protec- tion of the bonded phase resists degradation caused by such mobile phases. This material has also been shown to be stable when operated at temperatures up to 90 °C. These characteristics are particularly important for use in methods that need long-term stability and reproducibility.


Agilent ZORBAX Rapid Resolution High Definition SB-C18 Threaded Column handbook(1) - cover page
Brand
Agilent
Category
Other
Document type
Datasheet
Language
English
Pages
2
File format
PDF
File size
88 KB
Published
04 July, 2012
Updated
30 September, 2023
Model
SB-C18
MD5 checksum
52A97B51595588D562E173E07E8D0A71

About this manual

This document provides technical specifications and usage guidelines for Agilent ZORBAX Rapid Resolution High Definition (RRHD) SB-C8 threaded columns. Designed for use with ultra-high performance liquid chromatographs (UHPLCs), these columns feature a StableBond C8 stationary phase packed onto high-purity ZORBAX porous silica microspheres. The packing is chemically stable and resistant to degradation from aggressive mobile phases, including those with pH < 2 or high ionic strength, making it suitable for basic, neutral, or acidic samples.

What's inside

  • General Description
  • Column Characteristics
  • Safety Considerations
  • Operational Guidelines
  • Mobile Phase Selection
  • Applications
  • Column Care
  • Storage Recommendations

Specifications

Maximum operating pressure1200 bar (17,000 psi)
Maximum operating temperature80 °C
Particle pore size80A
Compatible instrumentsAgilent 1290 Infinity LC
Stationary phase typeStableBond C8

Frequently asked questions

What is the recommended pH range for the column?

Avoid use of columns below pH 1.0 or above pH 8.0.

Can the column be operated at high temperatures?

Yes, it is stable when operated at temperatures up to 80 °C, particularly at low pH.

What solvent is recommended for long-term storage?

Long-term storage should be in a pure organic solvent, preferably 100% acetonitrile.

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