The document describes possible causes of retention time shifts in Agilent GC and provides solutions.
This document is part of the Agilent GC Troubleshooting Series, specifically addressing retention time shifts in gas chromatography. It outlines various potential causes for this issue, such as changes in column dimensions, leaks in the injector or gas lines, large changes in sample concentration, solvent incompatibility, inaccurate purge times, and column temperature variations.
It is probably due to changes in column length, as the old column may have been trimmed over time to a significantly shorter length.
Tighten the column fitting, septum nut, insert weldment nut, split vent trap housing, and gold seal fitting, then rerun the test.