Agilent 6140 High Throughput LC/MS Application Note for Impurity Identification in OD-PABA

This article introduces the application of the Agilent Technologies 6140 Single Quadrupole LC/MS High Throughput Mass Spectrometer. The Agilent 1200 Series Rapid Resolution Liquid Chromatography (RRLC) system is used to analyze the impurities of octyl dimethyl para-aminobenzoic acid (OD-PABA). The instrument has a high scan speed capability, which allows clear detection of the degradation product p-dimethylbenzoic acid. The background and usage of OD-PABA are also discussed in this article.

Brand: Agilent
Document type: Application Note
Language: English
Pages: 6
File format: PDF
File size: 156 KB
Published: 02 July, 2012
Updated: 28 September, 2023
MD5 checksum: 381F6A8D288F044C494374DCD7E8FDB5
PDF: Agilent 6140 High Throughput LC/MS Application Note for Impurity Identification in OD-PABA PDF

About this manual

The document describes an analysis of octyl dimethyl para-aminobenzoic acid (OD-PABA) for the presence of impurities. The study utilizes the Agilent 6140 Single Quadrupole LC/MS High Throughput Mass Spectrometer coupled with an Agilent 1200 Series Rapid Resolution Liquid Chromatography system.

What's inside

Abstract
Introduction
Experimental
LC/MS Method Details
Results and Discussion
Conclusions

Frequently asked questions

What scan speed is required to clearly see the impurity peak at 0.707 minutes?

The impurity is only clearly seen at a scan speed of 10,000 amu/sec.

Which Agilent mass spectrometer model features the Ultra Fast Scan mode?

The Agilent 6140 Single Quadrupole Mass Spectrometer is the unique system with this capability.

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