This application note describes a method for the analysis of aromatic amines in leather extracts using CE-MS. This method provides specific identification of analytes in complex matrices that would present difficulties for HPLC. Organic extracts of leather fit this description exactly, therefore CE-MS is the method of choice.
The document explains that leather must be treated with chemicals before manufacturing goods like shoes and jackets. Some suppliers continue to use toxic aromatic amines, which can be hazardous upon skin contact. Consequently, monitoring these compounds is essential.
CE-MS (Capillary Electrophoresis with Mass Spectrometry) is identified as the ideal method for identifying specific analytes in complex matrices where HPLC might struggle. The note details an experimental setup using an Agilent CE system equipped with DAD detection and ChemStation software to analyze leather extracts.
This analysis monitors toxic compounds because skin contact with treated leather goods can be hazardous.
CE-MS is the method of choice because organic extracts of leather present difficulties for HPLC.
The experiment was performed at a voltage of +30 kV and a temperature of 20°C.